How Calcium May Interact With Bisphosphonates

02.10.2012

The occurrence of side effects or unwanted, potentially harmful reactions that come in addition to the desired effect of a certain medications, has long been well established by medical experts as possibly imminent in every pharmaceutical.

As inadvertent, non-beneficial effects may be an impending aspect of a drug treatment, some people may wish to utilize non-pharmaceuticals in fighting a certain disease, medical experts say. A handful of individuals may proactively take preventive measures through vitamins and minerals supplementation in potentially minimizing their risk of a particular disease. Others may use supplementation in combination of medications as part of their treatment. However, little do most people may have perceived that as were over-the-counter or prescription drugs, overconsumption of certain nutrients, as well as interaction with different medications may also involve problems to physical and overall health.

Aside from a prescription medication, patients with muscoskeletal deficiencies including osteoporosis or Paget’s disease of the bone, may also be advised to a bone-healthy diet rich in calcium and vitamin D, medical experts say. Other individuals may also be advised of calcium supplementation as part of their treatment plan. Although calcium is essential to optimal bone health, it has also been recognized as among the nutrients that may potentially cause an interaction when used with certain medications such as bisphosphonates or antiresorptive bone drugs.

Most individuals suffering from poor bone health may perceive calcium as a supplement that would well when taken with bisphosphonates. On the contrary, calcium may actually intervene and significantly decrease the body’s absorption of bisphosphonates that may render the bisphosphonate treatment less than effective. Most patients under bisphosphonate therapy are advised to take both medication and supplement at different times of the day, or take calcium at least two hours before or after bisphosphonates.

Getting educated of the potential risks that may come in a drug therapy including the risk of drug interaction and inadvertent effects is vital in establishing the safety and efficacy of a treatment. Where osteoporosis drugs are involved, several potential health risks including fractures have been linked to Fosamax and other bisphosphonates, which in some situations have reportedly initiated legal battles among former users and the drug manufacturer.

Sources:
osteoporosis.emedtv.com/calcium/calcium-drug-interactions-p2.html
umm.edu/altmed/articles/calcium-000945.htm
mayoclinic.com/health/calcium-supplements/MY01540/NSECTIONGROUP=2
webmd.com/food-recipes/features/effects-of-taking-too-many-vitamins?page=2

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